Solid Pseudopapillary Tumors of the Pancreas: Mayo Clinic 20 Years' Experience

Introduction: Solid pseudopapillary tumor (SPT) of the pancreas is a rare female predominant pancreatic neoplasm with favorable prognosis. Complete removal usually curative, and recurrences or mortalities are uncommon. This study aimed to present Mayo clinic experience SPT in 20-year cohort emphasizing clinical presentations, pathological features predictors outcomes. one largest single institution cohorts be published for SPT. Method: Individuals undergoing Pancreatectomies at Clinic between 01/2000 12/2020 were identified via electronic institutional databases. Demographic, clinical, operative postoperative details as well recurrence survival patterns abstracted retrospectively analyzed. Results: 51 patients had during time period, 46(90.2%) women median age was 28 years. The most common presenting symptom abdominal pain 26(51%) patients. Tumor location within spread equally head/body/tail size 4.1 centimeters. 29(57%) distal/subtotal Pancreatectomy, 16(31%) Whipple procedure, 3(6%) central 2(4%) enucleations 1(2%) total Pancreatectomy. With follow-up 5.8 years, 5(9.8%) there no related mortality. Potential malignant such local invasion/vascular involvement/positive lymph nodes/perineural invasion found 11(22%) Positive resection margins adjacent organ significantly associated (P=0.003 P<0.001 respectively). Conclusions: these should followed closely.